Myristin - Cetyl MO Canine Joint Formula by EHP Products

Members of the American Holistic Veterinary Medical Association have been using Myristin® since 1996 for dogs, cats, and horses. No side effects associated with this supplement, it is safe for dogs as well as cats. Myristin® Cetyl MO Canine Joint Formula, from EHP Products, provides joint relief for hip dysplasia and arthritis, and improves your dog's comfort and mobility. It also can be used to prevent the onset of joint problems. The formula is a combination of the best joint health products, including Glucosamine Sulfate and MSM, along with the signature ingredient of Cetyl Myristoleate.

How Cetyl Myristoleate (CMO) Came About — Cetyl Myristoleate was discovered by the late Harry Diehl, a research chemist at the National Institute of Health (NIH). In addition to isolating Cetyl Myristoleate and more than 500 other first-time compounds, Diehl is also known for discovering a method for synthesizing the unique sugar form used in the preparation of Dr. Jonas Salk’s oral polio vaccine During Diehl's research on arthritis, he discovered that he was unable to induce arthritis in a particular species of Swiss albino mice. He theorized that these particular mice carried a special trait that helped prevent the onset of arthritis—and he eventually was able to isolate Cetyl Myristoleate as the secret compound. Diehl was unable to generate much interest in his findings, and the information went largely untapped for 30 years. He was eventually awarded three patents for the use of CMO in connection with several forms of joint health problems.

What Makes Cetyl Myristoleate (CMO) so Unique — Cetyl Myristoleate (CMO) is a esterified fatty acid derived from myristoleic acid—and is the key ingredient in Myristin® Cetyl MO Canine Joint Formula. It is quite different from other joint-rebuilding nutrients, working in four unique and beneficial ways to enhance joint health and performance:

1.	CMO helps to regulate or “calm down” the body’s immune response to joint irritation—enhancing joint recovery and minimizing damage from pain and stress-inducing activities.
2.	CMO acts as an anti-inflammatory, helping to reduce the symptoms of inflammatory arthritis and other conditions in which inflammation can slow recovery, further tissue damage, increase pain and restrict motion.
3.	CMO stimulates joint lubrication to help relieve stiffness and improve joint mobility and range of motion.
4.	CMO has an analgesic or pain-killing effect that reduces joint pain and raises your dog’s level of comfort.

Although the exact mechanisms are not known at this time, there are some very strong indications that Cetyl Myristoleate (CMO), a fatty acid ester, is incorporated into the lipid layers of cell membranes. One theory is that if the method by which immune cells communicate is altered by reprogramming cell membrane receptor sites, these fatty acid esters could redirect a misdirected immune response. Another theory is that this group of fatty acid esters reprograms immune cells that have lived long beyond their normal life span. All cells in the body are programmed to die within a certain range of time. This preprogrammed cell death is called apoptosis. If this program has been modified in any way, these immune cells can produce damage and anything that would help to reprogram apoptosis would have benefits in joint health.

EHP Products, Inc. is the family company of the discoverer of Cetyl Myristoleate (CMO), Harry W. Diehl. EHP Products has been marketing CMO since 1996, and is known throughout the natural products world as the highest quality, low price supplier of CMO. Selling the "gold standard" of CMO, EHP is the owner of the U.S. Patents on CMO: #5,569,676 (1996) and #4,049,824 (1977). In fact, EHP provides the makers of Response Products' Cetyl M with CMO to make their joint formulas.

We sold Cetyl M for almost 2 years, but upon further examination wondered why the amount of Cetyl Myristoleate (CMO) was doubled in their products for people, as compared to that of dogs. So we tried selling the people version to dog folks. But, Response Products refused to allow us to proceed. This led us to EHP Products, since they were actually involved with CMO's discovery, and were providing it to Response Products. EHP sold their human products for years to veterinarian offices to use with animals, merely providing alternate dosage levels. And, they continue to do so. However, in 2008 they came out with their own canine version (essentially the same as their human version, but with the addition of flavor enhancers to produce a chewable).

So, how do the canine versions of Cetyl M & Myristin (Cetyl MO) COMPARE, you ask? Well . . . . .
►	Myristin has twice the amount per tablet of Cetyl Myristoleate than Cetyl M for canines does.
►	Myristin is approximately 2/3 the price of Cetyl M for canines.
►	Myristin is more cost-effective, as fewer bottles are needed for a full loading amount for dogs.
►	Myristin is a complete joint formula with Glucosamine and MSM, whereas Cetyl M for dogs lacks MSM in its formulation.
►	Myristin's formula includes vitamins and minerals. Cetyl M's formula does not.
►	Myristin's formula includes Curcumin, known for its antitumor, antioxidant, anti-arthritic & anti-inflammatory properties. Cetyl M's formula does not.
►	Myristin comes directly from the source and family of its discoverer, Harry W. Diehl. EHP Products has the longest tenure of any company in providing Cetyl Myristoleate to the world market.

Given the above comparison, we are NO LONGER providing Response Products' Canine Cetyl M version. Once we got the scoop, we placed our remaining Response Product bottles on deep discount to make up for the fact that their product was comparatively so overpriced. While their version is certainly acceptable, its accompanying formulation is not nearly as robust and the quantity of CMO is so little that folks had to buy twice as much. Quality, better health & education—NOT PROFIT—is what we are all about so it was actually pretty easy to decide to go solely with Myristin. Beginning January 5, 2009, we are providing Myristin® Special Canine Joint Formula in two convenient sizes, 120 chewables and 240 chewables.

Myristin® Special Canine Joint Formula
Two convenient sizes, 120 chewables and 240 chewables. US Shipping only. Price for 120 is $41.95, and for 240 it is $79.95.

Feeding Instructions for Dogs:

► Loading Period: Feed 1 tablet daily per 25 lbs. of body weight for 8 weeks. Best given before the time of a regular daily feeding.

► Maintenance Period: Switch to ½ tablet daily per 25 lbs. of body weight. For severe cases or senior dogs, continue at initial dosage.

► Monitor your dog's condition and adjust levels for optimum results.

► Be sure to provide access to clean, fresh water at all times.

Feeding Instructions for Cats:

► 1 tablet daily for 8 weeks, then ½ tablet daily as maintenance amount. Tablets may need to be crushed and given on food.

LEARN MORE BELOW: learn
Myristin® Cetyl MO Canine Joint Formula Information Sheet
Makers of Myristin® Cetyl MO Canine Joint Formula Answer your TOP 10 Questions
Medical and Research Articles

Myristin® Cetyl MO Canine Joint Formula Information Sheet info

Ingredients	Contents (per tablet)	Myristin® Cetyl MO Ingredient Characteristics — What they are and what they do
Cetyl Myristoleate (CMO)	500 mg CMO Complex	►Cetyl Myristoleate (CMO) is a unique fatty acid ester incorporated into lipid layers of cell membrane ►Cetyl Myristoleate (CMO) often referred to as nature’s WD-40 for joints because of its lubricating qualities
Glucosamine Sulfate	300 mg	►An amino sugar that is important precursor for glycosylated proteins and lipids needed for joint health ►Precursor for glycosaminoglycans, a major component of joint cartilage ►Sulfate preferred form as it provides the sulfate molecule, a key building block for joint health
MSM (Methylsulfonyl Methane)	300 mg	►Found in small amounts in many foods ►Necessary building block for proteins, especially those found in connective tissue of the joints and skin ►An excellent source of bio-available dietary sulfur, an element that plays a critical role in maintaining the integrity and elasticity of connective and other tissues
Bromelain	18 mg	►Comes from the stem and part of the pineapple fruit ►Contains enzymes that digest protein (proteases), also a natural blood thinner & anti-inflammatory agent
Curcumin (Turmeric)	6.3 mg	►According to the National Cancer Institute, curcumin blocks the formation of reactive-oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclo-oxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C. These effects may play a role in curcumin's anti-neoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer. ►Dr. Kidd's Guide to Herbal Dog Care: believes tumeric has anticancer properties, anti-inflammatory properties, antimicrobial characteristics, cardiovascular system benefits (inhibits platelet aggregation and interferes with intestinal cholesterol uptake), and intestinal benefits (decreases gas formation).
Vitamin C	150 mg	►An essential nutrient required for growth and repair of tissues in all parts of body ►Necessary to form collagen, this protein used to make skin, tendons, ligaments & blood vessels ►Essential for healing of wounds, and repair and maintenance of cartilage, bones, and teeth
Manganese Citrate elemental MN 2.9mg	10 mg	►A mineral with a role in joint health ►Helps body absorb vitamin B1 and E
Lipase 15,000 FIP/gm	33 mg	►An enzyme with a role in digestion of fats ►Helps in absorption of Cetyl Myristoleate (CMO)
Lecithin	100 mg	►Phosphatidyl choline ►Plays a role in absorption of Cetyl Myristoleate (CMO)
Natural Prime Rib of Beef	320 mg	►Tablets are chewable and highly palatable, with all-natural flavorings of prime of beef, chicken, and bacon ►Tasty tablets can even be used as treats as dogs will eat them readily ►Some competitors’ joint formulas are not able to use MSM in their products because dogs do not like the taste of MSM. High amounts of natural flavorings mask the MSM taste, so Myristin® Cetyl MO Canine Formula is a complete joint formula which makes it very cost-effective and easy to administer.
Natural Chicken Flavor	80 mg
Natural Bacon Flavor	40 mg

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Makers of Myristin® Cetyl MO Answer your TOP 10 Questions Answer

1. Where is Cetyl Myristoleate (CMO) found in nature?
Cetyl Myristoleate (CMO) is found in sperm whales, mice, and beavers. Myristin, EHP’s registered brand name of CMO, is produced synthetically in an organics plant in the U.S. Fatty acids derived from the large-scale commercial manufacture of oleic acid are used as the source for myristoleic acid.

2. How is Myristin® Cetyl MO Canine Joint Formula taken?
Cetyl Myristoleate (CMO) is best taken on an empty stomach about 30-45 minutes before meals. However, it is fine to take Myristin® after meals if you wish. Most animals take Myristin® for two months, after which no more may be needed for a year or two, but some individuals may need to take another two month course sooner, and some may need a regular maintenance course.

3. How long until Myristin® Cetyl MO Canine Joint Formula starts working?
The first signs are commonly seen two to three weeks after treatment begins, but can take longer depending on the nature and severity of the animal's condition and other variables. This is a serious treatment that acts on joint tissues at the cellular level to enhance joint structure and tissue function. As such, it is not designed to simply “mask” symptoms and should not be viewed as a “quick fix.” The recommended time and dosage for the initial “loading” period and subsequent maintenance program are based on averages. In nature, of course, there is no such thing as “average.” Be sure to monitor your dog’s condition closely and adjust as necessary to help ensure optimum results.

4. How long do I have to give Myristin® Cetyl MO Canine Joint Formula to my dog?
The answer to this question is impossible to know for certain, depending on the nature and severity of your dog's condition—and your treatment goals. For chronic conditions, such as arthritis, we recommend an ongoing maintenance program for continued relief. For more acute conditions, such as a specific injury, treatment may continue until the joint has fully recovered. In these situations, Myristin® Cetyl MO Canine Joint Formula is often administered post-recovery to slow or prevent the onset of arthritis in the injured joint. For active animals where joints are subjected to higher levels of stress, particularly large dogs, the formula is often used as a preventative treatment to enhance performance, minimize the damaging effects of stress on joint tissues, and increase the life of the joint and the comfort of the dog.

5. Are there any side effects?
There are no known side effects with Myristin® Cetyl MO Canine Joint Formula. All ingredients are naturally occurring and formulated to enhance joint function. There are no synthetic compounds, drugs or medications of any kind. Veterinarians have prescribed Myristin® since its introduction in 1996 to promote joint health, relief and performance in dogs without restriction.

6. Will Myristin® Cetyl MO Canine Joint Formula interfere with other medications?
No. Veterinarians have been using this formula since its introduction in 1996 to promote joint health, relief and performance in dogs without restriction.

7. Do I have to give a “loading” dose if my dog is already on glucosamine?
Yes. Cetyl Myristoleate effects and acts upon joint tissues in ways that are unique to Cetyl Myristoleate—and DIFFERENT than glucosamine. One does not work as a substitute for the other. In Myristin® Cetyl MO Canine Joint Formula, Cetyl Myristoleate and Glucosamine HCL work in concert with other joint-enhancing ingredients to deliver the greatest benefit to your dog. We recommend an initial “loading” dose be 8 weeks for dogs. The recommended “loading” period and dosage level are based on averages. In nature, of course, there is no such thing as “average.” Be sure to monitor your dog’s condition and adjust as may be necessary to help ensure optimum results.

8. Can my dog use Myristin® with the medications s/he uses regularly?
Yes. While there are no known contraindications or interactions with Myristin®, it is always a good practice to consult with your healthcare professional before starting on something new.

9. Can my dog take Myristin® Cetyl MO Canine Joint Formula if s/he has Allergies?
Myristin® contains no preservatives. It contains no sodium, no sugar, no soy and no cholesterol. It has not been known to cause allergic reaction in anyone. If you have a history of severe allergies, it is always a good idea to consult with your healthcare professional before starting to take anything new.

10. Why is EHP's Myristin® Cetyl MO Canine Joint Formula the best value?
Myristin® has been marketed by the family of Harry W. Diehl since 1996. EHP Products has by far the longest tenure of any company in providing Cetyl Myristoleate (CMO) to the world market. The quality and quantity of CMO in our products has never been in doubt, since Harry W. Diehl always checked our products for us before his death. In checking the CMO content of other companies' products, there was sometimes far less than the labeled amount. You can count on Myristin® to be a product that contains what the label says at a low price.

Not all labels of CMO products comply with FDA label regulations, and in such cases it is impossible for the consumer to know the CMO content. For example, the CMO product of one of the nation's largest dietary supplement companies lists "Cetyl Myristoleate Proprietary Blend, 1100 mg" (this amount is in two capsules). This label makes it appear as if the amount of CMO is 1100 mg, while the actual amount of CMO per capsule is approximately 70 mg.

Also, do not be misled by exaggerated or confusing claims of the amount of CMO per capsule or softgel. It is difficult for encapsulators to get more than 550 mg of CMO powder in a 00 size capsule. With 20% CMO powder, this would yield 110 mg per capsule. Websites or product labels that claim larger quantities of Cetyl Myristoleate, such as actual websites claiming 380 mg or 500 mg of CMO, are misleading, since the cited quantity is the amount of the mixed Cetyl esters, not actual Cetyl Myristoleate.

Being Cautious: If the label does not state the exact amount of Cetyl Myristoleate and the other significant Cetyl esters, such as Cetyl myristate, Cetyl oleate, and so forth; or, if you call the distributors and they cannot or will not tell you the per cent of Cetyl Myristoleate in the mixture of Cetyl esters; or, if there is not even a phone number where you can ask someone, BEWARE, for you may not be getting the CMO bargain that you think you are getting. You can count on EHP for quality and integrity when it comes to buying CMO.

Watch out for Cetyl Myristate Products: Some products contain Cetyl myristate as the main ingredient, not Cetyl Myristoleate, so be sure you are buying genuine Cetyl Myristoleate. Cetyl myristate is an ester of myristic acid, which is plentiful in vegetable sources Cetyl myristate can be made cheaply due to the large quantities of myristic acid in nature. Cetyl myristate is not the same as Cetyl Myristoleate. Unfortunately, some companies have marketed Cetyl myristate with claims or labels that lead the consumer to confuse it with Cetyl Myristoleate.

Watch out for Vegetable Source Claims: Some distributors claim that their product is from a vegetable source. At the present time there is only one known vegetable-derived commodity or article of commerce that contains commercially viable concentrations of myristoleic acid, a necessary ingredient in manufacture of Cetyl Myristoleate. This material is known as kombo butter, and it comes from the kombo nut, which is native to Sierra Leone and Gabon in Africa. Real Cetyl Myristoleate products can be made from the kombo nut, but, unfortunately, the concentration of Cetyl Myristoleate will be low (considerably less than 15%).

As a practical matter, almost all Cetyl Myristoleate is made by using myristoleic acid derived from fatty acids from the large-scale manufacture of oleic acid or other sources of bovine products. These fats are generally available and contain sufficient amounts of myristoleic acid. Anyone buying a Cetyl Myristoleate product claimed to be from a vegetable source should demand incontrovertible proof of the vegetable source, if one of the reasons for the purchase is the alleged vegetable source. If the distributor will not certify that the source of the myristoleic acid is kombo butter, then you will not be getting a bona-fide CMO vegetable product.

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